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CTCF 抗体

CTCF 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2461796
发货至: 中国
  • 抗原 See all CTCF 抗体
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    适用
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    人, 小鼠, 大鼠, 犬
    宿主
    • 46
    • 5
    • 1
    • 1
    克隆类型
    • 38
    • 15
    多克隆
    标记
    • 39
    • 2
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    This CTCF antibody is un-conjugated
    应用范围
    • 33
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CTCF.
    Top Product
    Discover our top product CTCF Primary Antibody
  • 应用备注
    CTCF antibody can be used for detection of CTCF by ELISA at 1:312500. CTCF antibody can be used for detection of CTCF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store CTCF antibody at -20 °C.
  • 抗原
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    别名
    CTCF (CTCF 产品)
    别名
    im:7152666 antibody, CTCF antibody, xctcf antibody, AW108038 antibody, CCCTC-binding factor antibody, CCCTC-binding factor (zinc finger protein) antibody, CTCF antibody, ctcf antibody, Ctcf antibody
    背景
    CTCF is a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in CTCF have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.
    分子量
    83 kDa
    基因ID
    10664
    NCBI登录号
    NP_006556
    UniProt
    P49711
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