PARP1 抗体
Our Local Distributor
北京 101111
Quick Overview for PARP1 抗体 (ABIN2460801)
抗原
See all PARP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Antibody is purified by protein A chromatography method.
-
免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP1.
-
-
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 81-390) antibody
PARP1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyKO Validated PARP1 适用: 人 WB, ICC, IF, IP, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibodyPARP1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibodyPARP1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 140-220), (Cleaved-Asp214) antibodyPARP1 适用: 人, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100) antibodyPARP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibodyPARP1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyPARP1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 8C7 unconjugated Recombinant Antibody
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibodyPARP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (N-Term) antibodyPARP1 适用: 人 WB, IHC, 2D-PAGE 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- PARP1 antibody can be used for detection of PARP1 by ELISA at 1:62500. PARP1 antibody can be used for detection of PARP1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
-
浓度
- 1 mg/mL
-
缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
-
注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PARP1 antibody at -20 °C.
-
-
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
-
别名
- PARP1
-
背景
- PARP1 encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
-
分子量
- 113 kDa
-
基因ID
- 57097
-
NCBI登录号
- NP_001609
-
UniProt
- P09874
-
途径
- Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
抗原
-
