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T-Box 19 抗体

TBX19 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2460437
发货至: 中国
  • 抗原 See all T-Box 19 (TBX19) 抗体
    T-Box 19 (TBX19)
    适用
    • 11
    • 7
    • 6
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    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 11
    • 1
    克隆类型
    • 10
    • 2
    多克隆
    标记
    • 12
    This T-Box 19 antibody is un-conjugated
    应用范围
    • 12
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX19.
    Top Product
    Discover our top product TBX19 Primary Antibody
  • 应用备注
    TBX19 antibody can be used for detection of TBX19 by ELISA at 1:312500. TBX19 antibody can be used for detection of TBX19 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store TBX19 antibody at -20 °C.
  • 抗原
    T-Box 19 (TBX19)
    别名
    TBX19 (TBX19 产品)
    别名
    TBX19 antibody, TBS19 antibody, TPIT antibody, dJ747L4.1 antibody, CH-TBXT antibody, TBXT antibody, AU019250 antibody, D1Ertd754e antibody, Tpit antibody, T-box 19 antibody, TBX19 antibody, Tbx19 antibody
    背景
    TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    分子量
    48 kDa
    基因ID
    9095
    NCBI登录号
    NP_005140
    UniProt
    O60806
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