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IL-15 抗体

IL15 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2459939
发货至: 中国
  • 抗原 See all IL-15 (IL15) 抗体
    IL-15 (IL15) (Interleukin 15 (IL15))
    适用
    • 57
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    人, 小鼠, 大鼠
    宿主
    • 71
    • 20
    • 4
    • 3
    • 2
    • 1
    克隆类型
    • 79
    • 22
    多克隆
    标记
    • 60
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    This IL-15 antibody is un-conjugated
    应用范围
    • 73
    • 37
    • 35
    • 18
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL15.
    Top Product
    Discover our top product IL15 Primary Antibody
  • 应用备注
    IL15 antibody can be used for detection of IL15 by ELISA at 1:312500. IL15 antibody can be used for detection of IL15 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store IL15 antibody at -20 °C.
  • 抗原
    IL-15 (IL15) (Interleukin 15 (IL15))
    别名
    IL15 (IL15 产品)
    别名
    IL15 antibody, AI503618 antibody, IL-15 antibody, interleukin 15 antibody, IL15 antibody, Il15 antibody
    背景
    IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
    分子量
    13 kDa
    基因ID
    3600
    NCBI登录号
    NP_751914
    UniProt
    P40933
    途径
    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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