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- 抗原 See all GALE 抗体
- GALE (UDP-Galactose-4-Epimerase (GALE))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GALE antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GALE.
- Top Product
- Discover our top product GALE Primary Antibody
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anti-UDP-Galactose-4-Epimerase (GALE) antibody
GALE 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-340) antibodyGALE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 142-171) antibodyGALE 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21189 unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 1-348) antibodyGALE 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 129-348) antibodyGALE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) antibodyGALE 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (AA 201-250) antibodyGALE 适用: 人, 犬, Pig, 兔, Cow, 马, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-UDP-Galactose-4-Epimerase (GALE) (N-Term) antibodyGALE 适用: 人, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- GALE antibody can be used for detection of GALE by ELISA at 1:312500. GALE antibody can be used for detection of GALE by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store GALE antibody at -20 °C.
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- 抗原
- GALE (UDP-Galactose-4-Epimerase (GALE))
- 别名
- GALE (GALE 产品)
- 别名
- GALE antibody, im:7147391 antibody, wu:fb05f01 antibody, zgc:136578 antibody, F15H21.11 antibody, F15H21_11 antibody, REB1 antibody, ROOT EPIDERMAL BULGER1 antibody, ROOT HAIR DEFECTIVE 1 antibody, UDP-GLUCOSE 4-EPIMERASE antibody, UGE4 antibody, ECK0748 antibody, galD antibody, JW0742 antibody, SMU.888 antibody, BA5505 antibody, BA5700 antibody, VFA0352 antibody, galE antibody, 2310002A12Rik antibody, AI323962 antibody, 1n569 antibody, xgale antibody, SDR1E1 antibody, UDP-galactose-4-epimerase antibody, NAD(P)-binding Rossmann-fold superfamily protein antibody, UDP-galactose 4-epimerase GalE antibody, UDP-glucose 4-epimerase antibody, UDP-glucose 4-epimerase GalE antibody, UDP-glucose/UDP-N-acetylglucosamine 4-epimerase antibody, galactose-4-epimerase, UDP antibody, UDP-galactose-4-epimerase L homeolog antibody, GALE antibody, gale antibody, RHD1 antibody, ECs0787 antibody, galE antibody, galE1 antibody, galE2 antibody, STY0809 antibody, galE-2 antibody, SG0897 antibody, galD antibody, Ent638_1250 antibody, Gale antibody, gale.L antibody
- 背景
- GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.
- 分子量
- 38 kDa
- 基因ID
- 2582
- NCBI登录号
- NP_001008217
- UniProt
- Q14376
- 途径
- Response to Water Deprivation, Cellular Glucan Metabolic Process
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