电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Sphingomyelin Synthase 2 抗体

SGMS2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2459623
发货至: 中国
  • 抗原 See all Sphingomyelin Synthase 2 (SGMS2) 抗体
    Sphingomyelin Synthase 2 (SGMS2)
    适用
    • 25
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 23
    • 2
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    This Sphingomyelin Synthase 2 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SGMS2.
    Top Product
    Discover our top product SGMS2 Primary Antibody
  • 应用备注
    SGMS2 antibody can be used for detection of SGMS2 by ELISA at 1:1562500. SGMS2 antibody can be used for detection of SGMS2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SGMS2 antibody at -20 °C.
  • 抗原
    Sphingomyelin Synthase 2 (SGMS2)
    别名
    SGMS2 (SGMS2 产品)
    别名
    SMS2 antibody, 4933405A16Rik antibody, 5133401H06Rik antibody, AI854299 antibody, RGD1305778 antibody, spermatin antibody, sphingomyelin synthase 2 antibody, sgms2 antibody, SGMS2 antibody, Sgms2 antibody
    背景
    SGMS2 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. SGMS2 directly and specifically recognizes the choline head group on the substrate. SGMS2 also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. SGMS2 does not function strictly as a SM synthase. SGMS2 is required for cell growth.Sphingomyelin (SM) is a major component of plasma membranes. It is preferentially concentrated in the outer leaflet and has a role in the formation of lipid rafts. SM synthases (EC 2.7.8.27), such as SGMS2, produce SM in the lumen of the Golgi and on the cell surface through the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product (Huitema et al., 2004 [PubMed 14685263]).
    分子量
    42 kDa
    基因ID
    166929
    NCBI登录号
    NP_689834
    UniProt
    Q8NHU3
You are here:
客服