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NEK3 抗体

NEK3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2459259
发货至: 中国
  • 抗原 See all NEK3 抗体
    NEK3 (NIMA related kinase 3 (NEK3))
    适用
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    宿主
    • 57
    • 3
    克隆类型
    • 59
    • 1
    多克隆
    标记
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    This NEK3 antibody is un-conjugated
    应用范围
    • 53
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NEK3.
    Top Product
    Discover our top product NEK3 Primary Antibody
  • 应用备注
    NEK3 antibody can be used for detection of NEK3 by ELISA at 1:1562500. NEK3 antibody can be used for detection of NEK3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store NEK3 antibody at -20 °C.
  • 抗原
    NEK3 (NIMA related kinase 3 (NEK3))
    别名
    NEK3 (NEK3 产品)
    别名
    HSPK36 antibody, ATNEK3 antibody, NIMA-RELATED KINASE3 antibody, NIMA-related kinase 3 antibody, T8M17.60 antibody, T8M17_60 antibody, NIMA related kinase 3 antibody, NIMA (never in mitosis gene a)-related expressed kinase 3 antibody, NIMA-related kinase 3 S homeolog antibody, NIMA-related kinase 3 antibody, NEK3 antibody, Nek3 antibody, nek3.S antibody
    背景
    NEK3 is a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. It differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase.In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. The protein encoded by this gene is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. Three transcript variants have been found for this gene, but the full-length nature of only two of them has been characterized.
    分子量
    58 kDa
    基因ID
    4752
    NCBI登录号
    NP_002489
    UniProt
    P51956
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