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REC8 抗体

REC8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2459159
发货至: 中国
  • 抗原 See all REC8 抗体
    REC8 (REC8 Homolog (Yeast) (REC8))
    适用
    • 38
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    宿主
    • 52
    • 2
    克隆类型
    • 53
    • 1
    多克隆
    标记
    • 15
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    This REC8 antibody is un-conjugated
    应用范围
    • 53
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    • 3
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    • 1
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    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human REC8.
    Top Product
    Discover our top product REC8 Primary Antibody
  • 应用备注
    REC8 antibody can be used for detection of REC8 by ELISA at 1:1562500. REC8 antibody can be used for detection of REC8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store REC8 antibody at -20 °C.
  • 抗原
    REC8 (REC8 Homolog (Yeast) (REC8))
    别名
    REC8 (REC8 产品)
    别名
    Rec8L1 antibody, mrec antibody, HR21spB antibody, REC8L1 antibody, Rec8p antibody, REC8 meiotic recombination protein antibody, REC8 homolog (yeast) antibody, REC8 antibody, Rec8 antibody
    背景
    REC8 is required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
    分子量
    62 kDa
    基因ID
    9985
    NCBI登录号
    NP_005123
    UniProt
    O95072
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