PPP1R13B 抗体
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北京 101111
Quick Overview for PPP1R13B 抗体 (ABIN2459151)
抗原
See all PPP1R13B 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antibody is purified by peptide affinity chromatography method.
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免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPP1R13B.
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应用备注
- PPP1R13B antibody can be used for detection of PPP1R13B by ELISA at 1:312500. PPP1R13B antibody can be used for detection of PPP1R13B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PPP1R13B antibody at -20 °C.
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- PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
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别名
- PPP1R13B
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背景
- PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
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分子量
- 119 kDa
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基因ID
- 23368
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NCBI登录号
- NP_056131
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UniProt
- Q96KQ4
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途径
- p53 Pathway
抗原
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