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- 抗原 See all PILRB 抗体
- PILRB (Paired Immunoglobin-Like Type 2 Receptor beta (PILRB))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PILRB antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PILRB.
- Top Product
- Discover our top product PILRB Primary Antibody
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anti-Paired Immunoglobin-Like Type 2 Receptor beta (PILRB) (AA 20-191) antibody
PILRB 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired Immunoglobin-Like Type 2 Receptor beta (PILRB) (AA 51-150) antibodyPILRB 适用: 人 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Paired Immunoglobin-Like Type 2 Receptor beta (PILRB) antibodyPILRB 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Paired Immunoglobin-Like Type 2 Receptor beta (PILRB) (AA 146-195) antibodyPILRB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- PILRB antibody can be used for detection of PILRB by ELISA at 1:312500. PILRB antibody can be used for detection of PILRB by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PILRB antibody at -20 °C.
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- 抗原
- PILRB (Paired Immunoglobin-Like Type 2 Receptor beta (PILRB))
- 别名
- PILRB (PILRB 产品)
- 别名
- FDFACT1 antibody, FDFACT2 antibody, FDFACT antibody, Fdact antibody, Pilrb antibody, paired immunoglobin-like type 2 receptor beta antibody, paired immunoglobin-like type 2 receptor beta 1 antibody, PILRB antibody, Pilrb1 antibody, Pilrb antibody
- 背景
- Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. Alternative splicing has been observed at this locus and three variants, encoding two distinct isoforms, are described. Additional transcript variants have been identified but their full-length nature has not been determined.
- 分子量
- 23 kDa
- 基因ID
- 29990
- NCBI登录号
- NP_038468
- UniProt
- Q9UKJ0
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