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ATP2B4 抗体

ATP2B4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2458841
发货至: 中国
  • 抗原 See all ATP2B4 抗体
    ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))
    适用
    • 25
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 25
    • 2
    克隆类型
    • 25
    • 2
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    This ATP2B4 antibody is un-conjugated
    应用范围
    • 23
    • 18
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP2B4.
    Top Product
    Discover our top product ATP2B4 Primary Antibody
  • 应用备注
    ATP2B4 antibody can be used for detection of ATP2B4 by ELISA at 1:1562500. ATP2B4 antibody can be used for detection of ATP2B4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP2B4 antibody at -20 °C.
  • 抗原
    ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))
    别名
    ATP2B4 (ATP2B4 产品)
    别名
    ATP2B2 antibody, MXRA1 antibody, PMCA4 antibody, PMCA4b antibody, PMCA4x antibody, atp2b2 antibody, atp2b3 antibody, mxra1 antibody, pmca4 antibody, pmca4b antibody, pmca4x antibody, zgc:152801 antibody, ATP2B4 antibody, ATP2B1 antibody, Pmca4 antibody, ATPase plasma membrane Ca2+ transporting 4 antibody, ATPase, Ca++ transporting, plasma membrane 4 L homeolog antibody, ATPase, Ca++ transporting, plasma membrane 4 antibody, ATP2B4 antibody, atp2b4.L antibody, atp2b4 antibody, Atp2b4 antibody
    背景
    ATP2B4 belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. ATP2B4 is the plasma membrane calcium ATPase isoform 4.The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.
    分子量
    129 kDa
    基因ID
    493
    NCBI登录号
    NP_001001396
    UniProt
    B1APW5
    途径
    Ribonucleoside Biosynthetic Process
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