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ATP2B3 抗体

ATP2B3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2458839
发货至: 中国
  • 抗原 See all ATP2B3 抗体
    ATP2B3 (ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3))
    适用
    • 11
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 12
    克隆类型
    • 12
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    This ATP2B3 antibody is un-conjugated
    应用范围
    • 9
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP2B3.
    Top Product
    Discover our top product ATP2B3 Primary Antibody
  • 应用备注
    ATP2B3 antibody can be used for detection of ATP2B3 by ELISA at 1:312500. ATP2B3 antibody can be used for detection of ATP2B3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP2B3 antibody at -20 °C.
  • 抗原
    ATP2B3 (ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3))
    别名
    ATP2B3 (ATP2B3 产品)
    别名
    PMCA3 antibody, PMCA3a antibody, SCAX1 antibody, atp2b3 antibody, pmca3a antibody, zgc:92885 antibody, 6430519O13Rik antibody, Pmca3 antibody, ATPase plasma membrane Ca2+ transporting 3 antibody, ATPase, Ca++ transporting, plasma membrane 3a antibody, ATPase, Ca++ transporting, plasma membrane 3 antibody, plasma membrane calcium-transporting ATPase 2 antibody, ATP2B3 antibody, atp2b3a antibody, Atp2b3 antibody, atp2b3 antibody, LOC100639471 antibody
    背景
    ATP2B3 gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. ATP2B3 is the plasma membrane calcium ATPase isoform 3.The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced transcript variants encoding different isoforms have been identified.
    分子量
    134 kDa
    基因ID
    492
    NCBI登录号
    NP_001001344
    UniProt
    Q16720
    途径
    Ribonucleoside Biosynthetic Process
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