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HGF 抗体

HGF 适用: 人, 大鼠, 小鼠, 犬 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2458833
发货至: 中国
  • 抗原 See all HGF 抗体
    HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
    适用
    • 76
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    • 16
    • 7
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    人, 大鼠, 小鼠, 犬
    宿主
    • 65
    • 22
    • 4
    • 1
    克隆类型
    • 71
    • 21
    多克隆
    标记
    • 47
    • 13
    • 9
    • 3
    • 3
    • 2
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    • 2
    • 1
    • 1
    • 1
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    • 1
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    This HGF antibody is un-conjugated
    应用范围
    • 83
    • 33
    • 25
    • 14
    • 13
    • 13
    • 12
    • 10
    • 8
    • 6
    • 3
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    • 1
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    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HGF.
    Top Product
    Discover our top product HGF Primary Antibody
  • 应用备注
    HGF antibody can be used for detection of HGF by ELISA at 1:312500. HGF antibody can be used for detection of HGF by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store HGF antibody at -20 °C.
  • 抗原
    HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
    别名
    HGF (HGF 产品)
    别名
    DFNB39 antibody, F-TCF antibody, HGFB antibody, HPTA antibody, SF antibody, HGF antibody, C230052L06Rik antibody, HGF/SF antibody, NK1 antibody, NK2 antibody, SF/HGF antibody, hepatocyte growth factor antibody, HGF antibody, Hgf antibody
    背景
    Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69- kDa alpha-chain and 34- kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity.Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69- kDa alpha-chain and 34- kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
    分子量
    79 kDa
    基因ID
    3082
    NCBI登录号
    NP_001010932
    UniProt
    P14210
    途径
    RTK signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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