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- 抗原 See all HSBP1 抗体
- HSBP1 (Heat Shock Factor Binding Protein 1 (HSBP1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSBP1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSBP1.
- Top Product
- Discover our top product HSBP1 Primary Antibody
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anti-Heat Shock Factor Binding Protein 1 (HSBP1) (AA 1-75) antibody
HSBP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock Factor Binding Protein 1 (HSBP1) (AA 1-76) antibodyHSBP1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Heat Shock Factor Binding Protein 1 (HSBP1) antibody (HRP)HSBP1 适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-Heat Shock Factor Binding Protein 1 (HSBP1) antibody (FITC)HSBP1 适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-Heat Shock Factor Binding Protein 1 (HSBP1) antibody (Biotin)HSBP1 适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-Heat Shock Factor Binding Protein 1 (HSBP1) antibodyHSBP1 适用: 人, 小鼠, 大鼠, Cow, Pig WB, ICC, IF 宿主: 小鸡 Polyclonal unconjugated
anti-Heat Shock Factor Binding Protein 1 (HSBP1) antibodyHSBP1 适用: 人, 小鼠, 大鼠, Cow, Pig WB, ICC, IF 宿主: 小鼠 Monoclonal 6H11 unconjugated
anti-Heat Shock Factor Binding Protein 1 (HSBP1) (N-Term) antibodyHSBP1 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Heat Shock Factor Binding Protein 1 (HSBP1) (N-Term) antibodyHSBP1 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- HSBP1 antibody can be used for detection of HSBP1 by ELISA at 1:312500. HSBP1 antibody can be used for detection of HSBP1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store HSBP1 antibody at -20 °C.
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- 抗原
- HSBP1 (Heat Shock Factor Binding Protein 1 (HSBP1))
- 别名
- HSBP1 (HSBP1 产品)
- 别名
- HSBP1 antibody, npc-a-13 antibody, NPC-A-13 antibody, hsbp1 antibody, hsbp1a antibody, 0610007A03Rik antibody, AA408769 antibody, Hsp25 antibody, zgc:73224 antibody, heat shock factor binding protein 1 like 1 antibody, heat shock factor binding protein 1 antibody, Heat shock factor binding protein 1 antibody, heat shock factor binding protein 1 S homeolog antibody, heat shock factor binding protein 1 L homeolog antibody, heat shock factor binding protein 1b antibody, HSBP1L1 antibody, HSBP1 antibody, Bm1_07370 antibody, hsbp1.S antibody, hsbp1 antibody, hsbp1.L antibody, Hsbp1 antibody, hsbp1b antibody
- 背景
- The heat-shock response is elicited by exposure of cells to thermal and chemical stress and through the activation of HSFs (heat shock factors) results in the elevated expression of heat-shock induced genes. Heat shock factor binding protein 1 (HSBP1), is a 76-amino-acid protein that binds to heat shock factor 1 (HSF1), which is a transcription factor involved in the HS response. During HS response, HSF1 undergoes conformational transition from an inert non-DNA-binding monomer to active functional trimers. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulate HSF1 DNA-binding activity. Overexpression of HSBP1 in mammalian cells represses the transactivation activity of HSF1. When overexpressed in C.elegans HSBP1 has severe effects on survival of the animals after thermal and chemical stress consistent with a role of HSBP1 as a negative regulator of heat shock response.The heat-shock response is elicited by exposure of cells to thermal and chemical stress and through the activation of HSFs (heat shock factors) results in the elevated expression of heat-shock induced genes. Heat shock factor binding protein 1 (HSBP1), is a 76-amino-acid protein that binds to heat shock factor 1 (HSF1), which is a transcription factor involved in the HS response. During HS response, HSF1 undergoes conformational transition from an inert non-DNA-binding monomer to active functional trimers. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulate HSF1 DNA-binding activity. Overexpression of HSBP1 in mammalian cells represses the transactivation activity of HSF1. When overexpressed in C.elegans HSBP1 has severe effects on survival of the animals after thermal and chemical stress consistent with a role of HSBP1 as a negative regulator of heat shock response.
- 分子量
- 8 kDa
- 基因ID
- 3281
- NCBI登录号
- NP_001528
- UniProt
- O75506
- 途径
- SARS-CoV-2 Protein Interactome
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