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KCNN2 抗体

KCNN2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2458148
发货至: 中国
  • 抗原 See all KCNN2 抗体
    KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))
    适用
    • 25
    • 15
    • 15
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 15
    • 9
    • 1
    • 1
    克隆类型
    • 17
    • 9
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This KCNN2 antibody is un-conjugated
    应用范围
    • 11
    • 9
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNN2.
    Top Product
    Discover our top product KCNN2 Primary Antibody
  • 应用备注
    KCNN2 antibody can be used for detection of KCNN2 by ELISA at 1:62500. KCNN2 antibody can be used for detection of KCNN2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNN2 antibody at -20 °C.
  • 抗原
    KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))
    别名
    KCNN2 (KCNN2 产品)
    别名
    KCNN2 antibody, SK2 antibody, KCa2.2 antibody, SKCA2 antibody, SKCa 2 antibody, hSK2 antibody, fri antibody, potassium calcium-activated channel subfamily N member 2 antibody, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 antibody, KCNN2 antibody, Kcnn2 antibody
    背景
    KCNN2 is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This protein is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for KCNN2.Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN2 is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP.Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene.
    分子量
    26 kDa
    基因ID
    3781
    NCBI登录号
    NP_740721
    UniProt
    Q6PJI0
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