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- 抗原 See all NFX1 抗体
- NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NFX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Antibody is purified by peptide affinity chromatography method.
- 免疫原
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFX1.
- Top Product
- Discover our top product NFX1 Primary Antibody
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anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (AA 981-1080) antibody
NFX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (C-Term) antibodyNFX1 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 猴 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (N-Term) antibodyNFX1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) (Middle Region) antibodyNFX1 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- NFX1 antibody can be used for detection of NFX1 by ELISA at 1:62500. NFX1 antibody can be used for detection of NFX1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- 注意事项
- As with any antibody avoid repeat freeze-thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFX1 antibody at -20 °C.
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- 抗原
- NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
- 别名
- NFX1 (NFX1 产品)
- 别名
- NFX1 antibody, NFX2 antibody, 1300017N15Rik antibody, 3000003M19Rik antibody, NFX.1 antibody, TEG-42 antibody, Tex42 antibody, nuclear transcription factor, X-box binding 1 antibody, nuclear transcription factor, x-box binding 1 antibody, NFX1 antibody, CpipJ_CPIJ011986 antibody, nfx1 antibody, Nfx1 antibody
- 背景
- NFX1 binds to the X-box motif of MHC class II genes and represses their expression. NFX1 may play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. NFX1 mediates E2-dependent ubiquitination.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
- 分子量
- 113 kDa
- 基因ID
- 4799
- NCBI登录号
- NP_667344
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