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DUSP12 抗体

DUSP12 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2457984
发货至: 中国
  • 抗原 See all DUSP12 抗体
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    适用
    • 35
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 32
    • 3
    克隆类型
    • 35
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP12 antibody is un-conjugated
    应用范围
    • 27
    • 16
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Antibody is purified by peptide affinity chromatography method.
    免疫原
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DUSP12.
    Top Product
    Discover our top product DUSP12 Primary Antibody
  • 应用备注
    DUSP12 antibody can be used for detection of DUSP12 by ELISA at 1:1562500. DUSP12 antibody can be used for detection of DUSP12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    注意事项
    As with any antibody avoid repeat freeze-thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store DUSP12 antibody at -20 °C.
  • 抗原
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    别名
    DUSP12 (DUSP12 产品)
    别名
    DUSP12 antibody, dusp12 antibody, zgc:114069 antibody, MGC154526 antibody, DUSP1 antibody, YVH1 antibody, 1190004O14Rik antibody, AA027408 antibody, AW049275 antibody, ESTM36 antibody, LMW-DSP4 antibody, T-DSP4 antibody, VH1 antibody, mVH1 antibody, GKAP antibody, dual specificity phosphatase 12 antibody, dual specificity phosphatase 12 L homeolog antibody, Dual specificity protein phosphatase 12 antibody, dual specificity protein phosphatase 12 antibody, DUSP12 antibody, dusp12 antibody, dusp12.L antibody, GL50803_36315 antibody, MGYG_01770 antibody, Dusp12 antibody
    背景
    DUSP12 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.
    分子量
    38 kDa
    基因ID
    11266
    NCBI登录号
    NP_009171
    UniProt
    Q9UNI6
    途径
    Regulation of Carbohydrate Metabolic Process
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