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PRNP 抗体

PRNP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7A1 unconjugated
产品编号 ABIN2452081
发货至: 中国
  • 抗原 See all PRNP 抗体
    PRNP (Prion Protein (PRNP))
    适用
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    宿主
    • 83
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    小鼠
    克隆类型
    • 74
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    单克隆
    标记
    • 49
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    This PRNP antibody is un-conjugated
    应用范围
    • 57
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    Western Blotting (WB), ELISA
    交叉反应 (详细)
    Does not react with mouse Prion. Not tested with other species
    纯化方法
    Purified
    过滤
    Sterile filtered
    免疫原
    Recombinant human PrP lacking GPI anchor expressed and purified from rabbit kidney cell line RK13.
    克隆位点
    7A1
    亚型
    IgG
    Top Product
    Discover our top product PRNP Primary Antibody
  • 应用备注
    1) Western blotting: ~0. 5 g/mL
    2) ELISA
    Other applications have not been tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, 50 % glycerol
    储存液
    Azide free
    储存条件
    -20 °C
    储存方法
    Upon arrival centrifuge briefly, aliquot and store at -20 C
  • Sakudo, Nakamura, Tsuji, Ikuta: "GPI-anchorless human prion protein is secreted and glycosylated but lacks superoxide dismutase activity." in: International journal of molecular medicine, Vol. 21, Issue 2, pp. 217-22, (2008) (PubMed).

  • 抗原
    PRNP (Prion Protein (PRNP))
    别名
    Prion Protein (PRNP 产品)
    别名
    ASCR antibody, AltPrP antibody, CD230 antibody, CJD antibody, GSS antibody, KURU antibody, PRIP antibody, PrP antibody, PrP27-30 antibody, PrP33-35C antibody, PrPc antibody, p27-30 antibody, Prn antibody, Prn-p antibody, prp antibody, cjd antibody, prion antibody, prp(c) antibody, MGC84114 antibody, PRP antibody, PRPC antibody, Prp antibody, SIP antibody, PRNP antibody, AA960666 antibody, AI325101 antibody, PrP antibody, PrPC antibody, PrPSc antibody, Prn-i antibody, Sinc antibody, prP27-30 antibody, prP33-35C antibody, PrP-1 antibody, PrP1 antibody, prnprs1 antibody, stPrP-1 antibody, zgc:123004 antibody, prion protein antibody, prion protein S homeolog antibody, prion protein b antibody, PRNP antibody, Prnp antibody, prnp.S antibody, prnpb antibody
    背景
    Prion protein PrP is a membrane glycosylphosphatidylinositol(GPI) anchored glycoprotein highly expressed in neuron and glia cells as well as immune and reproductive cells. Mutations in the octapeptide repeat regions as well as elsewhere in this gene have been associated with neurodegenerative diseases such as Creutzfeldt Jakob disease, fatal familial insomnia, Gerstmann Straussler disease, Huntington disease like 1, and kuru. The infectious isoform of PrPC, known as PrPSc, is able to convert normal PrPPC proteins into the infectious isoform, which is insoluble amyloid aggregate, by changing their. Mature PrP protein in human consists of 209 amino acids. Several forms exist, one cell surface form anchored via and two forms, which are responsible for appearance of multiple bands in SDS-PAGE.
    UniProt
    P04156
    途径
    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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