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- 抗原 See all PHLDA3 抗体
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
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抗原表位
- AA 1-31, N-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PHLDA3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Specific to human PHLDA3.
- 交叉反应 (详细)
- Not tested in other species.
- 产品特性
- The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.
- 纯化方法
- Purified
- 过滤
- Sterile filtered
- 免疫原
- Synthetic peptide corresponding to N terminal aa 1-31 of human PHLDA3
- 克隆位点
- 4B6
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product PHLDA3 Primary Antibody
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- 应用备注
- Other applications were not tested.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, 50 % glycerol
- 储存液
- Azide free
- 储存条件
- -20 °C/-80 °C
- 储存方法
- -20 C (For long term storage: -70 C)
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PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt." in: Cell, Vol. 136, Issue 3, pp. 535-50, (2009) (PubMed).
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PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt." in: Cell, Vol. 136, Issue 3, pp. 535-50, (2009) (PubMed).
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- 抗原
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
- 别名
- PHLDA3 (PHLDA3 产品)
- 别名
- TIH1 antibody, Tih1 antibody, si:dz182n13.5 antibody, zgc:92333 antibody, pleckstrin homology like domain family A member 3 antibody, pleckstrin homology like domain, family A, member 3 antibody, pleckstrin homology-like domain, family A, member 3 antibody, PHLDA3 antibody, Phlda3 antibody, phlda3 antibody
- 背景
- PHLDA3 (Pleckstrin homology-like domain family A member 3) is a small PH (Pleckstrin homology) domain-only protein (127 a.a. in human) that is highly conserved in vertebrates. Recently PHLDA3 was found to be a p53-regulated repressor of Akt hence it is speculated as a tumor suppressor. PHLDA3 also inhibits anchorage-independent cell growth. PHLDA3 gene is frequently lost in human lung endocrine tumors.
- UniProt
- Q9Y5J5
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