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Nestin 抗体

NES 适用: 小鼠 IHC, ICC 宿主: 大鼠 Monoclonal 7A3 unconjugated
产品编号 ABIN2452056
发货至: 中国
  • 抗原 See all Nestin (NES) 抗体
    Nestin (NES)
    适用
    • 129
    • 67
    • 47
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 103
    • 34
    • 4
    • 1
    • 1
    大鼠
    克隆类型
    • 108
    • 35
    单克隆
    标记
    • 61
    • 10
    • 10
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    This Nestin antibody is un-conjugated
    应用范围
    • 79
    • 49
    • 48
    • 47
    • 40
    • 39
    • 39
    • 28
    • 25
    • 15
    • 7
    • 6
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    特异性
    Specific to mouse Nestin.
    交叉反应 (详细)
    Not tested in other species.
    产品特性
    The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.
    纯化方法
    Purified
    过滤
    Sterile filtered
    免疫原
    Mouse E16 embryonic cerebral cortex extracts
    克隆位点
    7A3
    亚型
    IgG2b kappa
  • 应用备注
    1. Immunocytochemistry
    2. Immunohistochemistry
    This antibody doesn't work in immunoblotting.
    Other applications are not tested.

    This antibody is very useful for immunostaining of mouse embryonic brain because it is rat antibody. Rat antibody has very low background in immunostaining using mouse tissues and is also useful for double-staining with mouse and rabbit antibodies.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, 50 % glycerol
    储存液
    Azide free
    储存条件
    -20 °C
  • Gilyarov: "Nestin in central nervous system cells." in: Neuroscience and behavioral physiology, Vol. 38, Issue 2, pp. 165-9, (2008) (PubMed).

    Hockfield, McKay: "Identification of major cell classes in the developing mammalian nervous system." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 5, Issue 12, pp. 3310-28, (1986) (PubMed).

  • 抗原
    Nestin (NES)
    别名
    Nestin (NES 产品)
    别名
    paranemin antibody, NES antibody, AA166324 antibody, C78523 antibody, ESTM46 antibody, nestin antibody, nestin S homeolog antibody, NES antibody, nes.S antibody, Nes antibody, nes antibody
    背景
    Nestin is an intermediate filament protein that is expressed in stem cells and progenitor cells in the mammalian central nervous system (CNS) during development. Nestin is replaced in the adult organism by other intermediate filament proteins, however, it may be re-expressed under certain pathological conditions such as ischemia, inflammation, brain injury, and neoplastic transformation. Nestin has been detected in many kinds of tumors, especially in tumors derived from the CNS, therefore it is considered to be a marker for cancer stem cells in neurogenic tumors.
    UniProt
    Q6P5H2
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