Presenilin 2 抗体 (AA 34-45)
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Quick Overview for Presenilin 2 抗体 (AA 34-45) (ABIN2443734)
抗原
See all Presenilin 2 (PSEN2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 34-45
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原理
- Presenilin 2 (C term) Mouse Monoclonal Antibody (APS21)
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特异性
- The antibody recognizes the C-terminal region of Presenilin 2 with no cross-reactivity observed with Presenilin 1.
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免疫原
- aa 34-45
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亚型
- IgG1
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anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (C-Term) antibody
PSEN2 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) antibodyPSEN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 32-65), (N-Term) antibodyPSEN2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB30801 unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 39-51), (N-Term) antibodyPSEN2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (N-Term) antibodyPSEN2 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 33-48), (Intracellular), (N-Term) antibodyPSEN2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) antibodyPSEN2 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 319-334) antibodyPSEN2 适用: 人, 大鼠 WB, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 101-150) antibodyPSEN2 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, Bat, Hamster, Pig, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 2 (Alzheimer Disease 4) (PSEN2) (AA 275-325) antibodyPSEN2 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA 1:1000,WB 1:100,IF 1:1300,IHC 1:1300
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- If reconstituted with deionized water in 250μL: ELISA 1:1000, WB 1:100, IF 1:1300, IHC 1:1300. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized protein free tissue culture supernatant
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
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别名
- Presenilin 2
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背景
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PS-2, AD3LP, AD5, E5-1, STM-2, PSEN2
Presenilin is an integral membrane protein ubiquitously expressed in the brain, it is mainly expressed in neurons where it is localized in the endoplasmic reticulum. Mutations in the presenilin proteins (PSEN1, PSEN2) are linked to an inherited form of Alzheimer's disease in some patients by increasing the production of the longer form of amyloid-beta. Presenilins are thought to affect gamma-secretase by regulating amyloid precursor protein (APP) processing and cleavage of the Notch receptor.
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UniProt
- P49810
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途径
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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