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- 抗原 See all HMGCS1 抗体
- HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HMGCS1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Affinity purification
- 免疫原
- Synthetic peptide of human HMGCS1
- 亚型
- IgG
- Top Product
- Discover our top product HMGCS1 Primary Antibody
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anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 1-238) antibody
HMGCS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 293-467) antibodyHMGCS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 241-520) antibodyHMGCS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 360-520) antibodyHMGCS1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) antibodyHMGCS1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (Internal Region) antibodyHMGCS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 290-317) antibodyHMGCS1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20146 unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) antibodyHMGCS1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 1-520) antibodyHMGCS1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1) (AA 251-300) antibodyHMGCS1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig, Hamster, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.6 mg/mL
- 缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- 储存液
- Sodium azide
- 注意事项
- Avoid freeze / thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
- 别名
- HMGCS1 (HMGCS1 产品)
- 别名
- HMGCS antibody, zgc:56481 antibody, B130032C06Rik antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 1 antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 antibody, 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody, hydroxymethylglutaryl-CoA synthase antibody, 3-hydroxy-3-methylglutaryl-CoA synthase antibody, hydroxymethylglutaryl coenzyme A synthase antibody, 3-hydroxy-3-methylglutaryl-CoA synthase 1 S homeolog antibody, HMGCS1 antibody, hmgcs1 antibody, Hmgcs1 antibody, mvaS antibody, SAS2432 antibody, SZO_RS04705 antibody, SEQ_1109 antibody, NAEGRDRAFT_77778 antibody, hmgcs1.S antibody
- 背景
- HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalonate by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptional regulation by PPAR, RXR, COUP-TF and HNF-4.
- NCBI登录号
- NP_001091742
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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