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PTAFR 抗体

PTAFR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2432185
发货至: 中国
  • 抗原 See all PTAFR 抗体
    PTAFR (Platelet-Activating Factor Receptor (PTAFR))
    适用
    • 43
    • 29
    • 20
    宿主
    • 42
    • 1
    克隆类型
    • 43
    多克隆
    标记
    • 13
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTAFR antibody is un-conjugated
    应用范围
    • 36
    • 22
    • 17
    • 13
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human PTAFR
    亚型
    IgG
    Top Product
    Discover our top product PTAFR Primary Antibody
  • 应用备注
    IHC 1:25-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    Avoid freeze / thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PTAFR (Platelet-Activating Factor Receptor (PTAFR))
    别名
    PTAFR (PTAFR 产品)
    别名
    PAFR antibody, MGC52896 antibody, MGC160177 antibody, PAFr antibody, pafr antibody, PAF-R antibody, platelet activating factor receptor antibody, platelet-activating factor receptor antibody, platelet activating factor receptor L homeolog antibody, PTAFR antibody, Ptafr antibody, ptafr.L antibody, ptafr antibody
    背景
    This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants.
    NCBI登录号
    NP_000943
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin
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