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AVEN 抗体

AVEN 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2431089
发货至: 中国
  • 抗原 See all AVEN 抗体
    AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
    适用
    • 48
    • 13
    • 6
    • 3
    人, 小鼠
    宿主
    • 46
    • 2
    克隆类型
    • 45
    • 2
    多克隆
    标记
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This AVEN antibody is un-conjugated
    应用范围
    • 41
    • 22
    • 13
    • 13
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human AVEN
    亚型
    IgG
    Top Product
    Discover our top product AVEN Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:25-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    Avoid freeze / thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
    别名
    AVEN (AVEN 产品)
    别名
    AVEN antibody, pdcd12 antibody, aven antibody, wu:fc08c09 antibody, si:ch211-150c22.4 antibody, PDCD12 antibody, 1700013A01Rik antibody, 1700056A21Rik antibody, mAven-L antibody, mAven-S antibody, apoptosis and caspase activation inhibitor antibody, apoptosis, caspase activation inhibitor L homeolog antibody, apoptosis, caspase activation inhibitor antibody, Aven antibody, AVEN antibody, aven.L antibody, aven antibody
    背景
    AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1's ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.
    分子量
    Calculated MW: 39 kDa
    NCBI登录号
    NP_065104
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