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Aconitase 1 抗体

ACO1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2427037
发货至: 中国
  • 抗原 See all Aconitase 1 (ACO1) 抗体
    Aconitase 1 (ACO1)
    适用
    • 100
    • 45
    • 40
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 104
    • 3
    • 1
    克隆类型
    • 107
    • 1
    多克隆
    标记
    • 50
    • 12
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Aconitase 1 antibody is un-conjugated
    应用范围
    • 94
    • 39
    • 34
    • 27
    • 26
    • 20
    • 10
    • 10
    • 9
    • 4
    • 3
    • 2
    ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human ACO1
    亚型
    IgG
    Top Product
    Discover our top product ACO1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    Avoid freeze / thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Aconitase 1 (ACO1)
    别名
    ACO1 (ACO1 产品)
    别名
    ACONS antibody, IREB1 antibody, IREBP antibody, IREBP1 antibody, IRP1 antibody, Acon1 antibody, Ratireb antibody, ratireb antibody, Aco1 antibody, AI256519 antibody, Aco-1 antibody, Irebp antibody, Irp1 antibody, aconitase 1 antibody, aconitase 1, soluble antibody, aconitase 1 L homeolog antibody, ACO1 antibody, Aco1 antibody, aco1.L antibody
    背景
    Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
    NCBI登录号
    NP_002188
    途径
    Transition Metal Ion Homeostasis
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