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ARL6IP1 抗体

ARL6IP1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2422671
发货至: 中国
  • 抗原 See all ARL6IP1 抗体
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    适用
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    人, 小鼠
    宿主
    • 35
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    克隆类型
    • 37
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    多克隆
    标记
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    This ARL6IP1 antibody is un-conjugated
    应用范围
    • 26
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    ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human ARL6IP1
    亚型
    IgG
    Top Product
    Discover our top product ARL6IP1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    Avoid freeze / thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ARL6IP1 (ADP-Ribosylation Factor-Like 6 Interacting Protein 1 (ARL6IP1))
    别名
    ARL6IP1 (ARL6IP1 产品)
    别名
    arl6ip antibody, MGC56593 antibody, zgc:56593 antibody, zgc:77873 antibody, ARL6IP antibody, aip1 antibody, armer antibody, ARL6IP1 antibody, MGC85055 antibody, MGC139614 antibody, DKFZp459O112 antibody, AIP1 antibody, ARMER antibody, AIP-6 antibody, AL022945 antibody, AU042858 antibody, Aip-1 antibody, Arl6ip antibody, C85138 antibody, mKIAA0069 antibody, ADP-ribosylation factor-like 6 interacting protein 1 antibody, ADP ribosylation factor like GTPase 6 interacting protein 1 antibody, ADP ribosylation factor like GTPase 6 interacting protein 1 L homeolog antibody, ADP-ribosylation factor like GTPase 6 interacting protein 1 antibody, arl6ip1 antibody, ARL6IP1 antibody, arl6ip1.L antibody, Arl6ip1 antibody
    背景
    ARMER (apoptotic regulator in the membrane of the endoplasmic reticulum), also known as ADP-ribosylation-like factor 6-interacting protein 1 (ARL6IP1 or AIP1), is a multi-pass membrane protein that belongs to the Ras superfamily. It is expressed in brain, thymus, lung, bone marrow and, to a lesser extent, in spleen, kidney and liver. ARMER is not found in the heart and is found predominantly in early myeloid progenitor cells localizing to the intracytoplasmic membranes. It interacts with ARL6, inhibits caspase-9 activity by inhibiting proteolysis of downstream substrates (including LEHD-AFC, vimentin and caspase-3) and is down-regulated during myeloid differentiation. ARMER may play a role in membrane trafficking, protein transport or cell signaling during hematopoietic maturation.
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