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ARAP1 抗体 (AA 1190-1450)

ARAP1 适用: 人 WB, IP, IF 宿主: 小鼠 Monoclonal ARAP1-2 unconjugated
产品编号 ABIN238383
发货至: 中国
  • 抗原 See all ARAP1 抗体
    ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 1190-1450
    适用
    • 25
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 21
    • 3
    • 1
    小鼠
    克隆类型
    • 22
    • 3
    单克隆
    标记
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARAP1 antibody is un-conjugated
    应用范围
    • 12
    • 7
    • 5
    • 3
    • 3
    • 3
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
    特异性
    The antibody ARAP1-2 reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein.
    产品特性
    Synonyms: KIAA0782, Centaurin-delta-2, Arf-GAP, Rho-GAP domain, ANK repeat and PHdomain-containing protein 1
    纯化方法
    Protein A affinity chromatography
    免疫原
    His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1
    克隆位点
    ARAP1-2
    亚型
    IgG1
    Top Product
    Discover our top product ARAP1 Primary Antibody
  • 应用备注
    Suitable for Western Blotting (2 μg/mL). Immunoprecipitation. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4 with 15 mM sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze/thaw cycles.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))
    别名
    ARAP1 / CENTD2 (ARAP1 产品)
    别名
    CENTD2 antibody, ARAP1 antibody, Ci-ArfGAP-8 antibody, 2410002L19Rik antibody, Centd2 antibody, mKIAA0782 antibody, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 antibody, centaurin, delta 2 antibody, ARAP1 antibody, centd2 antibody, Arap1 antibody
    背景
    ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.Synonyms: ANK repeat and PH domain-containing protein 1, Arf-GAP, Centaurin-delta-2, KIAA0782, Rho-GAP domain
    基因ID
    116985
    UniProt
    Q96P48
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