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Desmoglein 1 抗体

DSG1 适用: 人 WB, IF, IP, IHC (fro) 宿主: 小鼠 Monoclonal 27B2 unconjugated
产品编号 ABIN2191993
发货至: 中国
  • 抗原 See all Desmoglein 1 (DSG1) 抗体
    Desmoglein 1 (DSG1)
    适用
    • 85
    • 23
    • 11
    • 4
    • 3
    • 2
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    • 1
    宿主
    • 56
    • 29
    • 1
    小鼠
    克隆类型
    • 51
    • 35
    单克隆
    标记
    • 37
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    This Desmoglein 1 antibody is un-conjugated
    应用范围
    • 47
    • 27
    • 26
    • 21
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    过滤
    0.2 μm filtered
    克隆位点
    27B2
    Top Product
    Discover our top product DSG1 Primary Antibody
  • 应用备注
    For immuno fluorescence and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
    限制
    仅限研究用
  • 缓冲液
    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    有效期
    12 months
  • 抗原
    Desmoglein 1 (DSG1)
    别名
    Desmoglein 1 (DSG1 产品)
    别名
    CDHF4 antibody, DG1 antibody, DSG antibody, PPKS1 antibody, SPPK1 antibody, DSG-1 antibody, DSG1 antibody, Dsg1b antibody, Dsg1c antibody, desmoglein 1 antibody, desmoglein 4 antibody, DSG1 antibody, DSG4 antibody, Dsg1 antibody
    背景
    Desmoglein 1 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity. The monoclonal antibody 27B2 reacts with the 165 kDa desmoglein 1 protein. Furthermore it is not cross reactive with desmoglein 2 or desmoglein 3.
    途径
    Cell-Cell Junction Organization
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