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TET2 抗体 (PE)

This anti-TET2 antibody is a 兔 多克隆 antibody detecting TET2 in FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2179566
发货至: 中国

Quick Overview for TET2 抗体 (PE) (ABIN2179566)

抗原

See all TET2 抗体
TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

适用

人, 小鼠, 大鼠

宿主

  • 47
  • 8
  • 1

克隆类型

  • 48
  • 8
多克隆

标记

  • 33
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TET2 antibody is conjugated to PE

应用范围

  • 34
  • 18
  • 11
  • 10
  • 7
  • 7
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
Flow Cytometry (FACS)
  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TET2

    亚型

    IgG
  • 应用备注

    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.

    说明

    Exitation/Emission: 480,565nm/578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4 °C for 12 months.
  • 抗原

    TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

    别名

    TET2

    背景

    TET2 is a 2,002 amino acid protein that is expressed in a variety of tissues, including brain, kidney, heart, lung, muscle and stomach, and exists as three alternatively spliced isoforms. Murine TET2 is also known as protein Ayu17-449 and is thought to play a role in proper kidney development and overall kidney function, as well as in hormone secretion throughout the body. The gene encoding human TET2 maps to chromosome 4 and the gene encoding mouse TET2 maps to chromosome 3. Chromosome 4 encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Murine chromosome 3 houses over 1,300 genes, some of which express alcohol dehydrogenases (ADHs), sodium channel modifiers (SCNMs), interleukins (ILs) and Insulin receptor-related (IRR) proteins. Defects in chromosome 3-localized genes are associated with hereditary congenital facial paresis (HCFP), increased susceptibility to spontaneous colitis, HIV-1-associated nephropathy, decreased renal vascular health and malignant sporadic pancreatic endocrine tumors.
    Synonyms: Tet oncogene family member 2, Methylcytosine dioxygenase TET2, Probable methylcytosine dioxygenase TET2, Protein Ayu17 449, Tet 2, Tet oncogene 2, Tet oncogene family member 2, TET2, TET2_HUMAN.

    途径

    Warburg Effect
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