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CD51 抗体

ITGAV 适用: 小鼠 FACS, IP, Func 宿主: 大鼠 Monoclonal unconjugated
产品编号 ABIN217760
发货至: 中国
  • 抗原 See all CD51 (ITGAV) 抗体
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    适用
    • 94
    • 51
    • 22
    • 7
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 64
    • 31
    • 9
    大鼠
    克隆类型
    • 56
    • 47
    单克隆
    标记
    • 54
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD51 antibody is un-conjugated
    应用范围
    • 47
    • 46
    • 29
    • 26
    • 22
    • 15
    • 14
    • 14
    • 11
    • 8
    • 6
    • 4
    • 4
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    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
    特异性
    Recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
    纯化方法
    Protein G purified
    内毒素水平
    Low Endotoxin
    免疫原
    Cultured LAK cells from Balb/c mice.
    亚型
    IgG1
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  • 应用备注
    Approved: Flo (1:10 - 1:100), Func, IP

    Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.
    说明

    Target Species of Antibody: Mouse

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4.
    注意事项
    avoid freeze thaw cycles. Store undiluted.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
  • 抗原
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    别名
    ITGAV/Integrin Alpha V/CD51 (ITGAV 产品)
    背景
    Name/Gene ID: ITGAV
    Family: Integrin

    Synonyms: ITGAV, CD51, CD51 antigen, Integrin, alpha V, MSK8, Integrin Alpha V, Integrin alpha-V, VNRA, Vitronectin receptor, Integrin alphaVbeta3, VTNR
    基因ID
    3685
    UniProt
    P06756
    途径
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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