JNK 抗体 (pThr183, pTyr185) (Cy5.5)
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Quick Overview for JNK 抗体 (pThr183, pTyr185) (Cy5.5) (ABIN2177528)
抗原
See all JNK (MAPK8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr183, pTyr185
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human MAPK9 around the phosphorylation site of Thr183+Tyr185
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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别名
- MAPK8 +
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背景
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Synonyms: MAPK8/MAPK9phospho T183/Y185, Mapk9, C Jun kinase 2, C Jun N terminal kinase 2, JNK 2, JNK-2, JNK 55, JNK2 alpha, JNK2 beta, JNK2alpha, JNK2B, JNK2beta, JNK55, Jun kinase, MAP kinase 9, MAPK 9, Mitogen activated protein kinase 9, P54 alpha, P54aSAPK, PRKM9, SAPK alpha, SAPK1a, SAPKa, Stress activated protein kinase JNK2.
Background: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
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基因ID
- 5601
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途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
抗原
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