CD14 抗体
Quick Overview for CD14 抗体 (ABIN217653)
抗原
See all CD14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes the human CD14 cell surface antigen. CD14 is a 55 KDa glycoprotein that contains multiple leucine-rich repeats. It is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) linkage but a soluble form of CD14 also exists. CD14 is strongly expressed on the surface of monocytes and macrophages but has also been shown to be expressed on the surface of non-myeloid cells. CD14 functions as a pattern recognition receptor, in innate immunity for a variety of ligands, in particular for the LPS (endotoxin) of Gram-negative bacteria. Has been shown to block SDF-induced chemotaxis of U937 cells in a dose-dependent manner.
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纯化方法
- Protein G purified
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内毒素水平
- Low Endotoxin
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免疫原
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Type of Immunogen: Native protein -
亚型
- IgG2a
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应用备注
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Approved: ELISA, Flo (1:100 - 1:200), Func, WB
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS.
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注意事项
- Store undiluted.
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储存条件
- -20 °C
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储存方法
- -20°C. Store undiluted.
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- CD14
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别名
- CD14
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背景
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Name/Gene ID: CD14
Synonyms: CD14, CD14 Molecule, CD14 antigen -
基因ID
- 929
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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