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ERI1 抗体 (AA 51-150) (Alexa Fluor 555)

ERI1 适用: 小鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 555
产品编号 ABIN2175643
发货至: 中国
  • 抗原 See all ERI1 抗体
    ERI1 (Exoribonuclease 1 (ERI1))
    抗原表位
    • 14
    • 8
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 42
    • 32
    • 19
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    小鼠
    宿主
    • 56
    • 1
    克隆类型
    • 56
    • 1
    多克隆
    标记
    • 23
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERI1 antibody is conjugated to Alexa Fluor 555
    应用范围
    • 32
    • 27
    • 12
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human HEXO
    亚型
    IgG
    Top Product
    Discover our top product ERI1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ERI1 (Exoribonuclease 1 (ERI1))
    别名
    Hexo (ERI1 产品)
    别名
    THEX1 antibody, thex1 antibody, zgc:110635 antibody, hexo antibody, Eri-1 antibody, 3'HEXO antibody, HEXO antibody, 3'hexo antibody, 3110010F15Rik antibody, Thex1 antibody, eri-1 antibody, RGD1308378 antibody, exoribonuclease 1 antibody, three prime repair exonuclease 1 antibody, exoribonuclease 1 L homeolog antibody, 3'-5' exonuclease eri-1 antibody, ERI1 antibody, CpipJ_CPIJ003945 antibody, eri1 antibody, eri1.L antibody, Eri1 antibody, eri-1 antibody
    背景

    Synonyms: HEXO, THEX1, 3'HEXO, 3'-5' exoribonuclease 1, 3'-5' exonuclease ERI1, Eri-1 homolog, Histone mRNA 3'-end-specific exoribonuclease, Histone mRNA 3'-exonuclease 1, Protein 3'hExo, ERI1, 3'EXO

    Background: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

    基因ID
    90459
    UniProt
    Q8IV48
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