FAS 抗体
Quick Overview for FAS 抗体 (ABIN215840)
抗原
See all FAS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Recognizes the human cell surface antigen Fas (~43kD) expressed in various human cells, including myeloid cells, T lymphoblastoid cells and diploid fibroblasts. This antibody does not recognize TNF and does not cross-react with mouse Fas.
-
纯化方法
- Immunoaffinity purified
-
免疫原
- Human diploid fibroblast cell line FS-7.
-
亚型
- IgM
-
-
-
-
应用备注
-
Approved: Flo, ICC, WB
Usage: Suitable for use in Flow Cytometry, Western Blot, and Immunocytochemistry. Apoptosis: >15 ng/mL maximally induced apoptosis of human Jurkat cells with 80-90 % mortality after 24 hours of treatment. This lot has an ID50 of 1.0 ng/mL in apoptosis assays. Western Blot: 0.5-2 mg/mL. Immunocytochemistry: 5-10 mg/mL o. Flow cytometry: Use 20 mg/mL. Can be used for activation studies. -
说明
-
Target Species of Antibody: Human
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- PBS, 50 % glycerol.
-
-
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
-
别名
- CD95 / FAS
-
背景
-
Name/Gene ID: FAS
Family: TNF Receptor
Synonyms: FAS, ALPS1A, APO-1, APT1, Apo-1 antigen, APO-1 cell surface antigen, Apo11 antigen, Apoptosis antigen 1, CD95 antigen, Delta Fas/APO-1/CD95, Fas AMA, FAS1, Fasl receptors, FASLG receptor, FASTM, FAS 827dupA, Fasl receptor, TNFRSF6, CD95 -
基因ID
- 355
-
UniProt
- P25445
-
途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
-