CRYAB 抗体 (AA 1-175)
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- 抗原 See all CRYAB 抗体
- CRYAB (Crystallin, alpha B (CRYAB))
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抗原表位
- AA 1-175
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CRYAB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Recognizes alpha B crystallin, a 20kD water-soluble major structural protein and member of the heat shock protein family, designated HSPB5, which acts as a molecular chaperone and is believed to play a role in the maintenance of ocular lens transparency/refractive index. Besides the involvement of both alpha A and alpha B crystallin in the prevention of protein precipitation and cataract formation in the eye, alpha crystallins have also been demonstrated in other tissues including the heart, brain, kidney, spleen and thymus. Studies have shown that a mutation in alpha B crystallin is responsible for desmin-related myopathy (DRM) and cataract(1), and that alpha B crystallin is a major component of the astrocytic inclusions known as Rosenthal fibers (RFs), found in Alexander's disease.
- 纯化方法
- Protein G purified
- 免疫原
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Recombinant human alpha B crystallin (1-175aa) purified from E. coli.
Type of Immunogen: Recombinant protein - 克隆位点
- 2E8
- 亚型
- IgG2b
- Top Product
- Discover our top product CRYAB Primary Antibody
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- 应用备注
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Approved: ELISA, WB (1:1000 - 1:2000)
Usage: Western Blot: LS-C45027 detects a band of approximately 20kD in mouse eye cell lysates. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- 抗原
- CRYAB (Crystallin, alpha B (CRYAB))
- 别名
- CRYAB / Alpha B Crystallin (CRYAB 产品)
- 别名
- CMD1II antibody, CRYA2 antibody, CTPP2 antibody, CTRCT16 antibody, HSPB5 antibody, MFM2 antibody, Crya-2 antibody, Crya2 antibody, HspB5 antibody, AACRYA antibody, CRYAB antibody, cryab antibody, cryab2 antibody, wu:fe37f08 antibody, zgc:91937 antibody, crystallin alpha B antibody, crystallin, alpha B antibody, hypothetical protein antibody, crystallin, alpha B, a antibody, crystallin, alpha B, b antibody, CRYAB antibody, Cryab antibody, ZK1128.7 antibody, cryaba antibody, cryabb antibody
- 背景
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Name/Gene ID: CRYAB
Synonyms: CRYAB, Alpha-crystallin B chain, CRYA2, Crystallin, alpha B, CTPP2, Heat shock protein beta-5, HSPB5, Alpha B Crystallin, Alpha(B)-crystallin, Rosenthal fiber component, Heat-shock 20 kD like-protein - 基因ID
- 1410
- UniProt
- P02511
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