SERPINB9 抗体
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- 抗原 See all SERPINB9 抗体
- SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SERPINB9 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 特异性
- Specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kD intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone Detects a band of approximately 42kD under reducing conditions. Clone 7D8 is suitable for use in indirect Immunofluorescence.
- 无交叉反应
- 小鼠, 猪
- 纯化方法
- Protein G purified
- 免疫原
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Recombinant PI-9 produced in P. pastoris.
Type of Immunogen: Recombinant protein - 亚型
- IgG1
- Top Product
- Discover our top product SERPINB9 Primary Antibody
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anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 1-376) antibody
SERPINB9 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 1-376) antibodySERPINB9 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) antibodySERPINB9 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 279-375) antibodySERPINB9 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (Internal Region) antibodySERPINB9 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (Internal Region) antibodySERPINB9 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 1-376) antibodySERPINB9 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 279-375) antibodySERPINB9 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (Internal Region) antibodySERPINB9 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 122-150) antibodySERPINB9 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Approved: Flo (1:10 - 1:100), IHC, IHC-P (1:50), WB
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Membrane permeabilization is required for this application. Immunohistochemistry: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Histology Positive Control Tissue: Tonsil. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
- 别名
- SERPINB9 / PI9 (SERPINB9 产品)
- 别名
- SERPINB9 antibody, BB283241 antibody, CAP-3 antibody, CAP3 antibody, PI-9 antibody, PI9 antibody, Spi6 antibody, ovalbumin antibody, serpin family B member 9 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 9 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 9 antibody, Serpinb9 antibody, SERPINB9 antibody
- 背景
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Name/Gene ID: SERPINB9
Synonyms: SERPINB9, CAP-3, CAP3, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, Serpin B9, PI-9, PI9 - 基因ID
- 5272
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