APAF1 抗体 (AA 12-28)
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北京 101111
Quick Overview for APAF1 抗体 (AA 12-28) (ABIN205853)
抗原
See all APAF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-28
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特异性
- Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. AHP487 recognizes a 130kD band in Western blots.
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纯化方法
- Affinity purified
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免疫原
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Synthetic peptide corresponding to amino acids 12-28 of human Apaf1 ( AA 12-28 ).
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
- Approved: IHC, IHC-P, WB (1:1000 - 1:2000)
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Store undiluted.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
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- APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
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别名
- APAF1 / APAF-1
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背景
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Name/Gene ID: APAF1
Family: Apoptosis
Synonyms: APAF1, APAF-1, CED4, KIAA0413 -
基因ID
- 317
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UniProt
- O14727
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途径
- p53 Pathway, Apoptosis, Caspase Cascade in Apoptosis, Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
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