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Lipocalin 2 抗体 (AA 1-198) (FITC)

LCN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal FITC
产品编号 ABIN1993327
发货至: 中国
  • 抗原 See all Lipocalin 2 (LCN2) 抗体
    Lipocalin 2 (LCN2)
    抗原表位
    • 16
    • 13
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-198
    适用
    • 82
    • 30
    • 25
    • 4
    • 3
    • 1
    宿主
    • 86
    • 26
    • 5
    • 3
    • 1
    • 1
    克隆类型
    • 86
    • 36
    多克隆
    标记
    • 54
    • 17
    • 11
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lipocalin 2 antibody is conjugated to FITC
    应用范围
    • 60
    • 39
    • 38
    • 18
    • 14
    • 13
    • 13
    • 13
    • 12
    • 11
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human NGAL protein (1-198AA)
    亚型
    IgG
    Top Product
    Discover our top product LCN2 Primary Antibody
  • 应用备注
    Optimal working concentration should be determinde by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Lipocalin 2 (LCN2)
    别名
    LCN2 (LCN2 产品)
    别名
    LCN2 antibody, 24p3 antibody, MSFI antibody, NGAL antibody, AW212229 antibody, Sip24 antibody, lipocalin 2 antibody, LCN2 antibody, Lcn2 antibody
    背景

    Background: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

    Aliases: 24p3 antibody, 25 kDa alpha 2 microglobulin related subunit of MMP9 antibody, 25 kDa alpha-2-microglobulin-related subunit of MMP-9 antibody, Alpha 2 microglobulin related protein antibody, HGNC:6526 antibody, HNL antibody, Lcn 2 antibody, Lcn2 antibody, Lipocalin-2 antibody, Migration stimulating factor inhibitor antibody, MSFI antibody, Neutrophil gelatinase associated lipocalin antibody, Neutrophil gelatinase associated lipocalin precursor antibody, Neutrophil gelatinase-associated lipocalin antibody, NGAL antibody, NGAL_HUMAN antibody, Oncogene 24p3 antibody, Oncogenic lipocalin 24p3 antibody, p25 antibody, Siderocalin antibody, siderocalin LCN2 antibody, SV40 induced 24P3 protein antibody, Uterocalin antibody

    UniProt
    P80188
    途径
    Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
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