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IL4 Receptor 抗体 (Extracellular Domain)

IL4R 适用: 人 WB, ELISA, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 49-20 unconjugated
产品编号 ABIN198262
发货至: 中国
  • 抗原 See all IL4 Receptor (IL4R) 抗体
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    抗原表位
    • 16
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 53
    • 37
    • 22
    宿主
    • 67
    • 9
    • 2
    • 2
    • 1
    小鼠
    克隆类型
    • 72
    • 8
    • 1
    单克隆
    标记
    • 44
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This IL4 Receptor antibody is un-conjugated
    应用范围
    • 74
    • 25
    • 23
    • 15
    • 14
    • 13
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Recognizes human Interleukin-4 receptor subunit alpha, also known as CD124. CD124 is a 825 amino acid ~90kD type I single pass transmembrane glycoprotein bearing a single domain. Interleukin-4 Receptor form a heterodimeric complex with the, referred to as the IL-4 type-1 complex. The alpha subunit can also form the type-II complex through association with the IL-13 receptor alpha 1 subunit. The IL-4R complex acts as a receptor for both interleukin-4 and interleukin-13. IL-4 R is expressed by B cells, T cells, monocytes and macrophages. Is reported to block human cell surface IL-4 receptor mediated bioactivities induced by IL-4 or IL-13. An ND50 was observed at approximately 5-20 ng/mL in the presence of 0.2 ng/mL of IL-4 using the factor dependant human erythroleukemic cell line, TF-1.
    纯化方法
    Protein A purified
    免疫原
    Sf 21-derived, recombinant human interleukin 4 receptor, extracellular domain.
    克隆位点
    49-20
    亚型
    IgG1
    Top Product
    Discover our top product IL4R Primary Antibody
  • 应用备注
    Approved: ELISA (1:500 - 1:2000), Flo (1:20 - 1:80), IHC, IHC-P (1:40 - 1:125), WB (1:250 - 1:1000)

    Usage: Western Blot: Will detect human IL-4 R under non-reducing conditions.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide, 10 % trehalose
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    别名
    IL4R / CD124 (IL4R 产品)
    别名
    IL4R antibody, il-4ra antibody, zgc:113063 antibody, CD124 antibody, IL-4RA antibody, IL4RA antibody, Il4ra antibody, IL4 antibody, Il4r antibody, interleukin 4 receptor antibody, interleukin 4 receptor, tandem duplicate 1 antibody, interleukin 4 receptor, alpha antibody, IL4R antibody, il4r.1 antibody, Il4r antibody, Il4ra antibody
    背景
    Name/Gene ID: IL4R
    Family: Interleukin

    Synonyms: IL4R, CD124, CD124 antigen, IL-4RA, IL4R nirs variant 1, IL4RA, Interleukin 4 receptor, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha
    基因ID
    3566
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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