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Connexin 43/GJA1 抗体 (AA 365-369)

This anti-Connexin 43/GJA1 antibody is a 兔 多克隆 antibody detecting Connexin 43/GJA1 in WB 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN197506
发货至: 中国

Quick Overview for Connexin 43/GJA1 抗体 (AA 365-369) (ABIN197506)

抗原

See all Connexin 43/GJA1 (GJA1) 抗体
Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

适用

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人, 大鼠, 小鼠

宿主

  • 133
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克隆类型

  • 136
  • 9
多克隆

标记

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This Connexin 43/GJA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 365-369

    特异性

    This antibody detects endogenous levels of total Connexin 43 protein.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen

    免疫原

    Synthetic KLH conjugated Peptide sequence around amino acids 365~369 (R-A-S-S-R) from Human Connexin-43.
  • 应用备注

    Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % Sodium Azide, 50 % Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

    别名

    GJA1 / Cx43

    背景

    GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5.Synonyms: Connexin-43, GJAL, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein

    基因ID

    2697

    NCBI登录号

    NP_000156

    UniProt

    P17302

    途径

    MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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