NFKBIB 抗体 (pSer23)
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北京 101111
Quick Overview for NFKBIB 抗体 (pSer23) (ABIN197074)
抗原
See all NFKBIB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer23
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特异性
- IκB-β antibody detects endogenous levels of total IκB-β protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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免疫原
- The antiserum was produced against synthesized phosphopeptide derived from human IkappaB- beta around the phosphorylation site of serine 23 (L-G-SP-L-G ).
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anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 85-332) antibody
NFKBIB 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (pSer23) antibodyNFKBIB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 56-237) antibodyNFKBIB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) antibodyNFKBIB 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) antibodyNFKBIB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 56-145) antibodyNFKBIB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB235 unconjugated Recombinant Antibody
anti-NF-kappa-B inhibitor beta (NFKBIB) (N-Term) antibodyNFKBIB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (C-Term) antibodyNFKBIB 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry: 1: 50approx. 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS(without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
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别名
- NFKBIB / IKBB
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背景
- Three major forms of IkB-like molecules have been identified and each is characterized by multiple copies of ankyrin repeats. IkB-alpha and IkB-beta appear to be the major regulatory forms of IkB in most cells. These proteins interact with p65 or c-Rel containing forms of NFkB and block nuclear import by masking the nuclear localization sequences of NFkB. The activation of NFkB involves the inducible phosphorylation and subsequent degradation of IkB. Immunoblotting easily detects the hyper-phosphorylated forms of IkB-alpha, but not phosphorylated IkB-beta. Interestingly, IkB-alpha and IkB-beta mediate different NFkB responses. IkB-alpha appears to control more transient activation of NFkB in response to an inducer, while IkB-beta controls a persistent response. Bcl-3 interacts with p50 and p52 containing forms of NFkB, but rather than being an inhibitor it appears to function to stimulate transcription. The degradation of IkB is confirmed by immunoblotting.Synonyms: I-kappa-B-beta, IkB-B, IkB-beta, IkappaBbeta, NF-kappa-B inhibitor beta, TR-interacting protein 9, TRIP9, Thyroid receptor-interacting protein 9
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基因ID
- 4793
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NCBI登录号
- NP_001001716
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UniProt
- Q15653
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途径
- NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
抗原
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