Phospholipase C gamma 2 抗体 (pTyr753)
Quick Overview for Phospholipase C gamma 2 抗体 (pTyr753) (ABIN196907)
抗原
See all Phospholipase C gamma 2 (PLCG2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr753
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特异性
- AP02452PU antibody detects endogenous levels of PLC-gamma 2 only when phosphorylated at Tyrosine 753.
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纯化方法
- Affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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免疫原
- The antiserum was produced against synthesized phosphopeptide derived from Human PLCG2 around the phosphorylation site of tyrosine 753 (S-L-Yp-D-V).
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anti-Phospholipase C gamma 2 (PLCG2) (AA 1-300) antibody
PLCG2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 826-985) antibodyPLCG2 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2D9E8 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) antibodyPLCG2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-1265) antibodyPLCG2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-1265) antibodyPLCG2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1-1265) antibodyPLCG2 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (pTyr753) antibodyPLCG2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 826-985) antibodyPLCG2 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 1E10C11 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (pTyr753) antibodyPLCG2 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A8B6 unconjugated
anti-Phospholipase C gamma 2 (PLCG2) (AA 1201-1258) antibodyPLCG2 适用: 人 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- Phospholipase C gamma 2 (PLCG2)
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别名
- PLCG2
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背景
- PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCγ, PLCδ, and PLCε. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCγ2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-2, PLC-IV, PLC-gamma-2, Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2
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基因ID
- 5336
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NCBI登录号
- NP_002652
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UniProt
- P16885
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途径
- RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
抗原
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