Progesterone Receptor 抗体 (pSer190)
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- 抗原 See all Progesterone Receptor (PGR) 抗体
- Progesterone Receptor (PGR)
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抗原表位
- pSer190
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Progesterone Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- This antibody detects endogenous levels of Progesterone Receptor only when phosphorylated at Serine 190.
- 纯化方法
- Immunoaffinity Chromatography using epitope-specific phosphopeptide
- 免疫原
- Synthetic phosphopeptide derived from Human Progesterone Receptor around the phosphorylation site of Serine 190 (G-L-Sp-P-A).
- Top Product
- Discover our top product PGR Primary Antibody
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anti-Progesterone Receptor (PGR) (AA 1-110) antibody
PGR 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 5D10 unconjugated
anti-Progesterone Receptor (PGR) antibodyPGR 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Progesterone Receptor (PGR) (AA 166-411) antibodyPGR 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2E9F2 unconjugated
anti-Progesterone Receptor (PGR) (AA 166-411) antibodyPGR 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2E4B9 unconjugated
anti-Progesterone Receptor (PGR) antibodyPGR 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor (PGR) (AA 1-250) antibodyPGR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor (PGR) (AA 501-600) antibodyPGR 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor (PGR) (pSer190) antibodyPGR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor (PGR) (AA 483-571) antibodyPGR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PGR-2694 unconjugated
anti-Progesterone Receptor (PGR) (C-Term) antibodyPGR 适用: 人 WB, ELISA, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Suitable for use in Western blot (1: 500approx. 1: 1000) and Immunohistochemistry (1: 50approx. 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide, 50 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- Progesterone Receptor (PGR)
- 别名
- Progesterone Receptor (PGR 产品)
- 别名
- NR3C3 antibody, PR antibody, 9930019P03Rik antibody, BB114106 antibody, ENSMUSG00000074510 antibody, PR-A antibody, PR-B antibody, XPR-1 antibody, pgr antibody, xpr-2 antibody, LOC443444 antibody, PGR antibody, pg antibody, pr antibody, gb:dq017620 antibody, progesterone receptor antibody, progesterone receptor L homeolog antibody, PGR antibody, Pgr antibody, pgr.L antibody, pgr antibody
- 背景
- Progesteron receptors (PRs) are nuclear hormone receptors of the NR3C class, which also inculdes mineralocorticoid, glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-kappaB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary fland and receptor expression is induced by estrogen. Well established functions of progesterone receptores include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition, progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory center to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and druing pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22.Synonyms: NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR
- 分子量
- 99 kDa
- 基因ID
- 5241
- NCBI登录号
- NP_000917
- UniProt
- P06401
- 途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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