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ATG4D 抗体 (C-Term)

Name: ATG4D 抗体 (C-Term)
SKU: ABIN1944848
Availability: OutOfStock

This anti-ATG4D antibody (ABIN1944848) is a Rabbit Polyclonal antibody detecting ATG4D in WB, IF, IHC (p). Suitable for Human.

Western blot analysis of G4D Pab in Y79 cell lysate 1811c. (ATG4D 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ATG4D 抗体 (C-Term))

IHC (p)

Fluorescent image of cells stained with ATG4D (C-term) antibody. (ATG4D 抗体 (C-Term))

Cos7, HE, MEF, and Hela cells, left to right respectively. (ATG4D 抗体 (C-Term))

4 images

(4 references)

产品编号 ABIN1944848

发货至: 中国

Datasheet as PDF

Quick Overview for ATG4D 抗体 (C-Term) (ABIN1944848)

抗原

See all ATG4D 抗体

ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

适用

人

宿主

兔

克隆类型

多克隆

标记

This ATG4D antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB7567

抗原表位
15

15

8

7

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 441-470, C-Term

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This ATG4D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 441-470 amino acids from the C-terminal region of human ATG4D.

亚型

Ig Fraction
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43) antibody
ATG4D 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43), (N-Term) antibody
ATG4D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7563 unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 381-474) antibody
ATG4D 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (C-Term) antibody
ATG4D 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 220-249) antibody
ATG4D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7565 unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 227-257) antibody
ATG4D 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 326-356) antibody
ATG4D 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11866 unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (Center) antibody
ATG4D 适用: 人, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 42-71), (N-Term) antibody
ATG4D 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB14788 unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (pSer467) antibody
ATG4D 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:100. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Shintani, Klionsky: "Autophagy in health and disease: a double-edged sword." in: Science (New York, N.Y.), Vol. 306, Issue 5698, pp. 990-5, (2004) (PubMed).

Melvin: "Make Milwaukee safe for babies: the Child Welfare Commission and the development of urban health centers, 1911-1912." in: Journal of the West, Vol. 17, Issue 2, pp. 83-93, (1980) (PubMed).

Pontén, Westermark: "Properties of human malignant glioma cells in vitro." in: Medical biology, Vol. 56, Issue 4, pp. 184-93, (1978) (PubMed).

Westermark, Pontén, Hugosson: "Determinants for the establishment of permanent tissue culture lines from human gliomas." in: Acta pathologica et microbiologica Scandinavica. Section A, Pathology, Vol. 81, Issue 6, pp. 791-805, (1974) (PubMed).
抗原

ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

别名

ATG4D

背景

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

分子量

52922

基因ID

84971

NCBI登录号

NP_001268433, NP_116274

UniProt

Q86TL0

途径

Autophagy