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COL17A1 抗体 (Chain alpha 1)

COL17A1 适用: 人 WB, IF, IHC (fro), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN191526
发货至: 中国
  • 抗原 See all COL17A1 抗体
    COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))
    抗原表位
    • 14
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 507-548, Chain alpha 1
    适用
    • 39
    • 7
    • 2
    宿主
    • 41
    克隆类型
    • 38
    • 3
    多克隆
    标记
    • 17
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COL17A1 antibody is un-conjugated
    应用范围
    • 26
    • 25
    • 19
    • 13
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Human type XVII Collagen / BP180 (aa 507-548).
    纯化方法
    Protein G Chromatography
    免疫原
    Glutathione-S-transferase fusion protein containing the sequence of the immunodominant region of human type XVII collagen / BP180 (aa 507-548)
    Top Product
    Discover our top product COL17A1 Primary Antibody
  • 应用备注
    ELISA: 1/5000. Western blot: 1/500. Immunocytochemistry on Frozen Sections: 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in aqua bidest to a concentration of 1 mg/mL.
    浓度
    2.0 mg/mL
    缓冲液
    50 mM Tris, pH 7.4
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store lyophilized at 2-8 °C and reconstituted at -20 °C.
  • 抗原
    COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))
    Abstract
    COL17A1 产品
    别名
    col17a1 antibody, fk89a06 antibody, si:ch211-223p8.6 antibody, wu:fk89a06 antibody, COL17A1 antibody, BA16H23.2 antibody, BP180 antibody, BPA-2 antibody, BPAG2 antibody, LAD-1 antibody, Bpag antibody, Bpag2 antibody, collagen type XVII alpha 1 chain antibody, collagen, type XVII, alpha 1b antibody, collagen, type XVII, alpha 1 antibody, Col17a1 antibody, col17a1b antibody, COL17A1 antibody
    背景
    Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in the gene coding for collagen XVII are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD 1, is generated by proteolytic processing of the full length form. Two transcript variants, one resulting from alternative splicing in the 3' UTR, have been identified for this gene.Synonyms: 180 kDa bullous pemphigoid antigen 2, BP180, BPAG2, Bullous pemphigoid antigen 2, COL17A1, LABD97, LAD-1
    基因ID
    1308
    NCBI登录号
    NP_000485
    UniProt
    Q9UMD9
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