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TNFSF18 抗体

TNFSF18 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1888239
发货至: 中国
  • 抗原 See all TNFSF18 抗体
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    适用
    • 60
    • 29
    • 5
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 51
    • 10
    • 6
    克隆类型
    • 50
    • 15
    • 1
    多克隆
    标记
    • 35
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    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
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    This TNFSF18 antibody is un-conjugated
    应用范围
    • 53
    • 32
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
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    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    GITRL antibody was raised against purified recombinant human GITR ligand.
    Top Product
    Discover our top product TNFSF18 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    别名
    GITRL (TNFSF18 产品)
    别名
    Gitrl antibody, AITRL antibody, GITRL antibody, TL6 antibody, hGITRL antibody, TNLG2A antibody, tumor necrosis factor (ligand) superfamily, member 18 antibody, TNF superfamily member 18 antibody, Tnfsf18 antibody, TNFSF18 antibody
    背景
    The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kappaB and various mitogen-activated protein kinases.The glucocorticoid-induced tumor necrosis factor receptor (GITR) is an emerging member of this family that is expressed on CD4+ CD25+ regulatory T cells and appears to have crucial immune regulation functions.Its ligand GITRL is expressed in endothelial and antigen-presenting cells and can activate NF-kappaB, induce both pro- and anti-apoptotic effects, inhibit the suppressive activity of regulatory T cells, and co-stimulate responder T cells through GITR.Dominant negative forms of NIK and TRAF2 expressed in transfected 293 cells substantially inhibited NF-kappaB activation, suggesting that the GITRL-GITR pathway involves both NIK and TRAF2.
    Synonyms: AITRL
    UniProt
    Q9UNG2
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