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BCL10 抗体 (N-Term)

BCL10 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1888191
发货至: 中国
  • 抗原 See all BCL10 抗体
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    抗原表位
    • 17
    • 15
    • 10
    • 9
    • 8
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 101
    • 37
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 73
    • 28
    克隆类型
    • 61
    • 41
    多克隆
    标记
    • 46
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL10 antibody is un-conjugated
    应用范围
    • 76
    • 33
    • 31
    • 31
    • 27
    • 18
    • 13
    • 13
    • 12
    • 11
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Peptide corresponding to amino acids near the amino terminus of human Bcl10.
    Top Product
    Discover our top product BCL10 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
    别名
    Bcl-10 (BCL10 产品)
    别名
    CARMEN antibody, CIPER antibody, CLAP antibody, c-E10 antibody, mE10 antibody, BCL10 antibody, AI132454 antibody, BCL-10 antibody, C81403 antibody, ME10 antibody, cE10 antibody, bcl10 antibody, B-cell CLL/lymphoma 10 antibody, B-cell lymphoma/leukemia 10-like antibody, B cell leukemia/lymphoma 10 antibody, B-cell lymphoma/leukemia 10 antibody, BCL10 antibody, Bcl10 antibody, bcl10 antibody, LOC100223183 antibody
    背景
    Apoptosis is related to many diseases including cancer.Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2.A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP.Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene.Overexpression of Bcl10 induces JNK, p38, and NF-kappaB activation.Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing and induces apoptosis through caspase-9 activation.Bcl10 exhibits a variety of mutations in MALT lymphomas and in B and T cell lineage lymphomas indicating that it may be commonly involved in the pathogenesis of human malignancy.Bcl10 is expressed in many human and murine tissues and cell lines.
    Synonyms: CIPER, CLAP
    分子量
    31 kDa
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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