RAPGEF3 抗体 (N-Term)
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- 抗原 See all RAPGEF3 抗体
- RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAPGEF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应 （详细）
- At least two isoforms of EPAC1 are known to exist, this antibody will detect both isoforms. EPAC1 antibody is predicted to not cross-react with EPAC2.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- EPAC1 antibody was raised against an 18 amino acid peptide near the amino terminus of human EPAC1.
- Top Product
- Discover our top product RAPGEF3 Primary Antibody
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 1-881) antibody
RAPGEF3 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (C-Term) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 772-881) antibodyRAPGEF3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 1-200) antibodyRAPGEF3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 301-400) antibodyRAPGEF3 适用: 人, 大鼠 ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) antibodyRAPGEF3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (C-Term) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 772-881) antibodyRAPGEF3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 359-408) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 107-156) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))
- 别名
- EPAC1 (RAPGEF3 产品)
- 别名
- RAPGEF3 antibody, epac antibody, si:dkey-27m20.2 antibody, CAMP-GEFI antibody, EPAC antibody, EPAC1 antibody, HSU79275 antibody, bcm910 antibody, 2310016P22Rik antibody, 9330170P05Rik antibody, Epac antibody, Epac1 antibody, Rap guanine nucleotide exchange factor 3 antibody, Rap guanine nucleotide exchange factor 3 S homeolog antibody, Rap guanine nucleotide exchange factor (GEF) 3 antibody, RAPGEF3 antibody, rapgef3.S antibody, rapgef3 antibody, Rapgef3 antibody
- 背景
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EPAC1, also known as Rap guanine nuclear exchange factor 3 and cAMPGEF-I, is widely expressed but most prominently in brain, heart, kidney, pancreas, spleen, ovary, thyroid and spinal cord.EPAC1 is a cAMP-binding protein with intrinsic guanine nuclear exchange factor activity that couples cAMP production to the activation of Rap, a GTPase belonging to the Ras family.This activation of Rap influences numerous cellular processes such as integrin-mediated cell adhesion, vascular endothelial barrier formation, and cardiac myocyte gap junction formation.Recently, EPAC1 has been suggested to also be involved in the cAMP-dependent regulation of ion channel formation, intracellular Ca++ signalling, ion transporter activity, and exocytosis.
Synonyms: Rap guanine nuclear exchange factor 3, RAPGEF3, cAMPGEF-I, bcm910 - NCBI登录号
- NP_659099
- 途径
- cAMP Metabolic Process
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