CXXC4 抗体 (N-Term)
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- 抗原 See all CXXC4 抗体
- CXXC4 (CXXC Finger Protein 4 (CXXC4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CXXC4 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- CXXC4 antibody was raised against an 18 amino acid peptide near the amino terminus of human CXXC4.
- Top Product
- Discover our top product CXXC4 Primary Antibody
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anti-CXXC Finger Protein 4 (CXXC4) (AA 1-198) antibody
CXXC4 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CXXC Finger Protein 4 (CXXC4) (AA 158-185), (C-Term) antibodyCXXC4 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22171 unconjugated
anti-CXXC Finger Protein 4 (CXXC4) (AA 164-194), (C-Term) antibodyCXXC4 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-CXXC Finger Protein 4 (CXXC4) (N-Term) antibodyCXXC4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- CXXC4 (CXXC Finger Protein 4 (CXXC4))
- 别名
- CXXC4 (CXXC4 产品)
- 别名
- 9330210J02Rik antibody, C030003J12Rik antibody, Idax antibody, IDAX antibody, Xldax antibody, xIdax antibody, CXXC finger 4 antibody, CXXC finger protein 4 antibody, CXXC finger protein 4 S homeolog antibody, Cxxc4 antibody, CXXC4 antibody, cxxc4.S antibody
- 背景
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CXXC4 is zinc finger protein that binds directly to the PDZ domain of DVL1, a protein involved in the Wnt signaling pathway, through its C-terminal region.CXXC4's interaction with DVL1 competes with DVL1-AXIN binding, although the affinity of DVL1 for CXXC4 is lower than that for AXIN.In mouse fibroblasts, CXXC4 suppressed Wnt3a induction of beta-catenin and inhibited Wnt3a-dependent TCF4 activation, suggesting that CXXC4 acts as a negative regulator of the Wnt signaling pathway and functions between DVL and beta-catenin.Recent reports suggest that decreased CXXC4 expression is associated with kidney cancer metastasis, cell proliferation, reduced apoptosis in response to cancer drugs, and upregulation of genes involved with proliferation, invasion and cell survival, suggesting that CXXC4 plays a critical role in tumor progression in kidney cancer.
Synonyms: CXXC-type zinc finger protein 4, IDAX - NCBI登录号
- NP_079488
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