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FBXL20 抗体 (N-Term)

FBXL20 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1888092
发货至: 中国
  • 抗原 See all FBXL20 抗体
    FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
    抗原表位
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 15
    • 9
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    人, 大鼠, 小鼠
    宿主
    • 12
    • 2
    • 1
    克隆类型
    • 13
    • 2
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    This FBXL20 antibody is un-conjugated
    应用范围
    • 10
    • 9
    • 4
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid peptide near the amino terminus of the human SCRAPPER.
    Top Product
    Discover our top product FBXL20 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
    别名
    SCRAPPER (FBXL20 产品)
    别名
    Fbl2 antibody, Fbl20 antibody, fbl20 antibody, MGC81000 antibody, scrapper antibody, FBL2 antibody, 2610511F20Rik antibody, 4632423N09Rik antibody, AI849362 antibody, AL117906 antibody, C86145 antibody, Scr antibody, mKIAA4147 antibody, FBXL2 antibody, Fbxl2 antibody, F-box and leucine rich repeat protein 20 antibody, F-box and leucine-rich repeat protein 20 L homeolog antibody, F-box and leucine-rich repeat protein 20 antibody, F-box/LRR-repeat protein 20 antibody, putative fbxl20 antibody, F-box and leucine rich repeat protein 2 antibody, FBXL20 antibody, fbxl20.L antibody, LOAG_14232 antibody, LOC100080065 antibody, Smp_097020.1 antibody, FBXL2 antibody, Fbxl20 antibody
    背景
    Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif.SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases.Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane.Scrapper has orthologs in C.elegans, D.melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species.Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission.This identifies protein degradation as a mechanism for holding synaptic communication in check.
    Synonyms: F-box, Leucine rich repeat protein 20, FBXL20, FBl2, FBL20
    NCBI登录号
    NP_116264
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